Large volume of water used for hydrocarbon production and processing can be an ideal place for bacterial growth and survival. Presence of bacteria can affect the quality of the product, asset integrity and the overall safety of the operations. Therefore, it is important to have a well-defined microbial control program, involving mainly proactive approaches in control of microorganisms. Monitoring, using different detection techniques, and control, using appropriate biocide treatments, are important measures in the program. Different types of biocides are available for microbial control programs in different phases of oil and gas operations. Understanding the application of biocides, their efficacy, compatibility and sustainability are critical in proper selection of biocides. There is no readymade check list available for the biocide selection and this often invites erroneous outputs because of numerous steps and manual interferences in developing a conclusion. A selection score card, based on numerical points on each step, could help in the better selection procedure and minimize the manual interpretation for conclusions.