Nickel-based alloys with high chromium contents such as 50%Cr-50%Ni are known to be excellent resistance to sulfur attack in coal-fired and heavy oil-fired boilers. However commercial high-chromium nickel based alloys containing 40-50% chromium levels are not supplied except in product forms such as casting powder and duplex tube (co-extrusion of a duplex billet). Therefore the applications of these alloys are limited. MC alloy (Alloy 45Cr1Mo) which is composed of 45% chromium 1% molybdenum and balance nickel has been specifically developed for a wrought alloy with improved workability in spite of its high chromium content of 45%. Alloy 45Cr1Mo is easily fabricated into all product forms such as plate sheet wire and tube. In this paper the resistance of Alloy 45Cr1Mo to sulfur attack will be discussed and the applications of Alloy 45Cr1Mo for fossil fuel-burning power plants will be demonstrated.