Oilfield facilities are handling far more complex conditions than what was possible a few years ago. Many existing facilities are being operated well past their design life and new developments are often in harsher environments. To manage safe and reliable operations in such environments industry heavily relies on complex yet carefully engineered oilfield chemicals such as scale inhibitors drag reducing agents corrosion inhibitors and biocides. Prior to field implementation these chemicals are tested in laboratories to ensure their performance. These tests however typically focus on the individual performance of each chemical. An important element that is generally overlooked is the compatibility between chemicals which can critically impact the ability of the chemical to meet its desired function in the field. A study was conducted to evaluate the impact of chemical compatibility on chemical performance.This paper focuses on the compatibility results of simultaneous use of corrosion inhibitors with biocide scale inhibitor and drag reducing agents. Results have revealed that chemicals which are used together in the field can interfere with each other. In the case of corrosion inhibitor and biocide studied here the incompatibility was severe enough to render the corrosion inhibitor completely ineffective. These lab results have immediate implications for fields where such incompatible chemicals are deployed. These fields need to quickly switch to compatible chemicals in order to maintain proper corrosion protection.