The key to the alteration of conditions at a metal surface before the initiation of microbially induced corrosion (MIC) is the formation of a biofilm,Thus prevention of bacterial adhesion processes on metal surfaces would be one of the potential weapons to avoid MIC. Serum globulin and by-products were used to prevent bacterial adhesion on different corrosion resistant metal surfaces generally used as implantable biomaterials. In this paper an immunoglobulin combination (IgA, IgG and IgM) has been used to prevent the formation of Pseudomonas fluorescens (P. fluorescens) biofilms on carbon steel and two different types of stainles steel (SS), A marked inhibition of bacterial adhesion was found under different experimental conditions. Several microscopic techniques were used for assessing adhesion inhibition while the electrochemical behavior of the steels was evaluated by means of different electrochemical techniques applied in the presence and in the
absence of the immunoglobulins.
Keywords: biofilms, bioadhesion. preventingadhesion. MIC, immunoglobulins, IgA,IgG, stainlessteel, carbon steel