Tight refining margins, increased competition, and the need to avoid adverse publicity and fines due to environmental leaks make continued, safe, reliable operation extremely important. This paper presents a series of case studies where high nickel alloys {UNS N10276, UNS
N06022, UNS N06030, UNS N07718, UNS R30605, UNS R31233, UNS N10665, UNS N06200, UNS N12160, UNS R30188, UNS N06002, and UNS N07214} have been effectively used in certain refining units and equipment. Included are innovative and successful uses of these alloys in Crude Distillation Units (atmospheric and vacuum), Catalytic Cracking Light Ends Unit, Saturated Light Ends Dethanizer Tower Reboilers, Hydroprocessing Units, Catalytic Reformer Units, Continuous Catalytic Reformer Units, I-IF and H2SO4 Alkylation Units, Sour Water Stripper Units, Sulfur Recovery Units, Corrosion Probes, and Instrumentation Tubing.