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Tetrakis(hydroxymethyl)-phosphonium Sulfate (THPS) is a very common active ingredient in oil and gas biocides. While product labels provide broad guidelines application dosing the lowest effective dose of THPS is difficult to determine. Site water chemistry and bacteria biology variability will affect the dose need to achieve the desired level of bacteria population control. For these reasons biocide dose response studies are commonly conducted on solutions containing bacteria to determine the effect of treatments before application.
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