The formation of biofilms and resulting microbiologically influenced corrosion (MIC) is a significant contributor to corrosion in a wide range of industries particularly the oil and gas industry. It is well understood that microbial communities particularly SRB communities present in biofilms are key contributors to MIC events. In order to combat MIC both corrosion inhibitors and biocides are used to mitigate microorganism growth thereby assisting in corrosion prevention. However extended prevention and efficacy remains a significant challenge. In this regard a series of biocides were tested and compared for MIC prevention in a laboratory dynamic flow cell biofilm reactor under anaerobic conditions utilizing inoculum from produced waters. In particular an effective dual treatment approach was identified utilizing a novel film-forming quaternary amine and benchmarked versus current MIC control technologies. The results showed that the treatment approach results in extended MIC prevention via a combined effect of anodic inhibition and biocidal efficacy at the metal surface.