Multiphase systems present am imposing challenge from a standpoint of corrosion evaluation and prediction because of the need to synergistically capture the role of important environmental, flow and metallurgical variables and underlying mechanisms of corrosion. This paper focuses on a methodology to model fluid flow in order to assess wall shear stress in multiphase systems. Methods of determining wall shear stress for differing flow regimes are discussed. An experimental setup for multiphase flow and shear stress simulation is also detailed.