Calcite scaling downhole and on production equipment is a common problem in a large central California steam drive oil field. In the past, formation squeezes with scale inhibitors have given inconsistent results in mitigating scale deposition. A mathematical model was used to simulate scale inhibitor residual data from a squeeze treatment. The effects of variables such as inhibitor volume and concentration, water production, displacement and zone length on treatment life were investigated in order to improve the design of squeeze applications. An optimization program was developed based on inhibitor and overflush volumes as a function of produced water. The optimized design was applied to a well and the residual decline curve was accurately predicted. Subsequent squeezes in additional wells using the optimized design were also successful. Keywords: Squeeze treatment, squeeze simulation, squeeze optimization, mathematical model, calcite, scale inhibition